With the Bills’ run of five straight division titles ending in 2025 despite a seventh straight season with double-digit wins, Buffalo moves forward with a new head coach in Joe Brady and the same expectations to make it to a Super Bowl, something the Bills have failed to do every season since 1993 despite their recent success. Will a new coach, new defensive scheme and the same old MVP candidate at quarterback be enough to finally win the AFC?
We’re taking a look at everything you need to know before making Buffalo Bills futures bets below, including odds, trends, 2026 schedule,
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